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Endothelial dysfunction in aged humans is related with oxidative stress and vascular inflammation

✍ Scribed by Leocadio Rodríguez-Mañas; Mariam El-Assar; Susana Vallejo; Pedro López-Dóriga; Joaquin Solís; Roberto Petidier; Manuel Montes; Julián Nevado; Marta Castro; Carmen Gómez-Guerrero; Concepción Peiró; Carlos F. Sánchez-Ferrer

Book ID
111199533
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
459 KB
Volume
8
Category
Article
ISSN
1474-9718

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## Abstract ## Objective To investigate the effect of statins on vascular dysfunction in rat adjuvant‐induced arthritis (AIA). ## Methods Fluvastatin (5 mg/kg/day) was administered orally to rats with AIA, for 21 days after the onset of arthritis. The vasodilatory response to acetylcholine of ao