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Endothelial cells express a matrix protein which binds activated factor XII in a zink-independent manner

✍ Scribed by Schousboe, Inger


Book ID
118034932
Publisher
Schattauer
Year
2006
Tongue
English
Weight
340 KB
Volume
95
Category
Article
ISSN
0340-6245

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## Abstract Pregnancy‐Associated Plasma Protein‐A (PAPP‐A) proteolyses insulin‐like growth factor binding protein‐4 (IGFBP‐4), thereby regulating local IGF availability. Reduced PAPP‐A mRNA expression has been reported in ovarian cancer specimens compared to normal ovarian surface epithelial cells