Endothelial cell damage in rheumatoid disease correlates with complement consumption and immune complexes
β Scribed by A. D. Blann
- Book ID
- 104707152
- Publisher
- Springer
- Year
- 1991
- Tongue
- English
- Weight
- 109 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0172-8172
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## The complement subcomponent Clq mediates binding of immune complexes and aggregates to endothelial cells in vitro* The present studies were initiated to investigate whether soluble immune complexes, upon interaction with complement, can bind to endothelial cells. Human umbilical vein endothelia
## Abstract Immune complexes (ICs) were determined by the nonβcomplementβdependent L1210 radioimmune assay on 132 serum samples collected from 53 patients with a variety of cancers. Both the mean IC levels and frequency of positive tests were significantly greater in cancer patients (mean = 96Β±100