Endothelial cell-conditioned medium modulates the synthesis and structure of proteoglycans in vascular smooth muscle cells
โ Scribed by Parakat Vijayagopal; Henry P. Ciolino; Gerald S. Berenson
- Book ID
- 119121566
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 709 KB
- Volume
- 1135
- Category
- Article
- ISSN
- 0167-4889
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In this study, we investigated the effect of the extracellular matrix (ECM) secreted by vascular cells on proteoglycan (PG) synthesis by vascular smooth muscle cells in culture. PG synthesis of human aortic smooth muscle cells plated on plastic or the matrices derived from vascular endothelial cells
## Toulouse Cedex, (M.B.) France We have previously shown (Berrou et al., J. Cell. Phys., 137:430-438, 1988) that porcine endothelial cell-conditioned medium (ECCM) stimulates proteoglycan synthesis by smooth muscle cells from pig aorta. ECCM stimulation requires protein cores for glycosaminoglyca