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Endoscopic variceal ligation in prophylaxis of first variceal bleeding in cirrhotic patients with high-risk esophageal varices

✍ Scribed by C Lay; Y Tsai; C Y Teg; W S Shyu; W S Guo; K L Wu; K J Lo

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 180 KB
Volume: 25
Category: Article
ISSN: 0270-9139
DOI: 10.1002/hep.510250608

No coin nor oath required. For personal study only.

✦ Synopsis

phylactic endoscopic variceal ligation (EVL) might be an ideal

To determine the efficacy of endoscopic variceal ligatherapy. 13-17 tion (EVL) in prophylaxis on the rate of first esophageal The present study was thus designed to determine, in a variceal bleeding, we conducted a prospective, randomcontrolled and prospective manner, whether EVL therapy of ized trial in 126 cirrhotic patients with no history of high-risk varices will affect the risk of first variceal bleeding previous upper gastrointestinal bleeding and with and improve chances of survival of cirrhotic patients with no esophageal varices endoscopically judged to be at high previous bleeding from the upper gastrointestinal tract. risk of hemorrhage. The end-points of the study were bleeding and death. Life-table curves showed that pro-PATIENTS AND METHODS phylactic EVL significantly diminished the rate of variceal hemorrhage (12/62 [19%] vs. 38/64 [60%]; P Å .0001)

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