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Endoscopic monitoring of infliximab therapy in Crohn's disease

✍ Scribed by Clas-Göran af Björkesten; Urpo Nieminen; Ulla Turunen; Perttu E. Arkkila; Taina Sipponen; Martti A. Färkkilä

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
261 KB
Volume
17
Category
Article
ISSN
1078-0998

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## Background: So far, infliximab (ifx) therapy for the treatment of crohn's disease (cd) has generally been guided by clinical symptoms. data on treatment response as ascertained by endoscopy in ifx therapy are scarce. the aims of this study were to measure the endoscopic response rate during ifx

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Background: Fecal calprotectin and lactoferrin are promising noninvasive biomarkers for intestinal inflammation. In Crohn's disease (CD), during anti-TNF-alpha (TNF-␣) treatment, the clinical significance of these markers has, however, been insufficiently explored. Methods: Among CD patients receiv