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Endoplasmic reticulum stress induced by oxidative stress in retinal pigment epithelial cells

โœ Scribed by Shikun He; Jennifer Yaung; Yeong Hoon Kim; Ernesto Barron; Stephen J. Ryan; David R. Hinton


Publisher
Springer-Verlag
Year
2008
Tongue
English
Weight
258 KB
Volume
246
Category
Article
ISSN
0065-6100

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## Abstract Exposure to excessive levels of light induces photoreceptor apoptosis and has previously been used as a model for the study of retinal degeneration. During the light exposure, intracellular calcium levels increase, and reactive oxygen species (ROS) are generated, which have been shown t