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Endoplasmic reticulum (ER) stress inhibitor salubrinal protects against ceramide-induced SH-SY5Y cell death

✍ Scribed by Ting Gong; Qin Wang; Zheng Lin; Ming-long Chen; Guo-zhen Sun


Book ID
119194495
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
432 KB
Volume
427
Category
Article
ISSN
0006-291X

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## Abstract We investigated the effect of vanadate, a tyrosine phosphatase inhibitor, on cell death induced by peroxynitrite in human neuroblastoma SH‐SY5Y cells. Vanadate prevented cell death induced by 3‐morpholinosydnonimine (SIN‐1), a peroxynitrite donor; whereas SIN‐1‐induced cell death was no