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Endonucleases: new tools to edit the mouse genome

โœ Scribed by Wijshake, Tobias; Baker, Darren J.; van de Sluis, Bart


Book ID
121804289
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
753 KB
Volume
1842
Category
Article
ISSN
0925-4439

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Endonucleases: tools to correct the dyst
โœ Joel Rousseau; Pierre Chapdelaine; Sรฉbastien Boisvert; Luciana P. Almeida; Jacqu ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 529 KB

## Abstract ## Background Various endonucleases can be engineered to induce doubleโ€strand breaks (DSBs) in chosen DNA sequences. These DSBs are spontaneously repaired by nonhomologousโ€endโ€joining, resulting in microโ€insertions or microโ€deletions (INDELs). We detected, characterized and quantified