𝔖 Bobbio Scriptorium
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Endoneurial tube shrinkage in the distal segment of a severed nerve

✍ Scribed by S. Sunderland; K. C. Bradley

Book ID
102112604
Publisher
John Wiley and Sons
Year
1950
Tongue
English
Weight
466 KB
Volume
93
Category
Article
ISSN
0021-9967

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✦ Synopsis

Following severance of a nerve the section below the level of the injury undergoes a series of characteristic changes, the essential features of which are the degeneration and removal of the axon and its myelin sheath, the proliferation of Schwann cells and the conversion of the nerve fiber encircled by the endoneurium into a Schwann band, Schwann tube or endoneurial tube. Though the contents of the endoneurial tubes fluctuate in both quantity and composition throughout the various phases of degeneration they are, ultimately, entirely the products of Schwann cell proliferation.

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Cultured peripheral nervous system cells
Cultured peripheral nervous system cells support peripheral nerve regeneration through tubes in the absence of distal nerve stump
✍ H. D. Shine; P. G. Harcourt; R. L. Sidman πŸ“‚ Article πŸ“… 1985 πŸ› John Wiley and Sons 🌐 English βš– 706 KB

Axons of a cut peripheral nerve will grow across a gap ( < 10 mm in adult rodents) formed when the proximal and distal stumps are placed at opposite ends of an impermeable, inert tube, but will not grow to the end of a blind-ended tube in the absence of the distal stump Williams et al, 19841. Work r