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Endogenous production of reactive oxygen species is required for stimulation of human articular chondrocyte matrix metalloproteinase production by fibronectin fragments

โœ Scribed by Marcello Del Carlo; Daniel Schwartz; Elizabeth A. Erickson; Richard F. Loeser


Book ID
113630250
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
697 KB
Volume
42
Category
Article
ISSN
0891-5849

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## Abstract ## Objective S100 proteins have been implicated in various inflammatory conditions, including arthritis. The aims of this study were to determine whether chondrocytes produce S100A4 and whether S100A4 can stimulate the production of matrix metalloproteinase 13 (MMPโ€13) by articular cho