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Endogenous phospholipid metabolism in stimulated neutrophils differential activation by FMLP and PMA

✍ Scribed by Charles N. Serhan; M. Johan Broekman; Helen M. Korchak; Aaron J. Marcus; Gerald Weissman


Book ID
115755522
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
447 KB
Volume
107
Category
Article
ISSN
0006-291X

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A23 187 stimulates the metabolism of endogenous as well as exogenous arachidonic acid (AA) and eicosapentaenolc acid (EPA) to their corresponding leukotrienes in human neutrophils. In contrast, conflicting results have been obtained concerning the effect of FMLP on the metabolism of these fatty acid