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Endogenous Nkx2.2+/Olig2+ oligodendrocyte precursor cells fail to remyelinate the demyelinated adult rat spinal cord in the absence of astrocytes

โœ Scribed by Jason F. Talbott; David N. Loy; Ying Liu; Mengsheng S. Qiu; Mary Bartlett Bunge; Mahendra S. Rao; Scott R. Whittemore


Book ID
116458308
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
824 KB
Volume
192
Category
Article
ISSN
0014-4886

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โœ Hans S. Keirstead; Joel M. Levine; William F. Blakemore ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 342 KB

Elucidation of the response of oligodendrocyte progenitor cell populations to demyelination in the adult central nervous system (CNS) is critical to understanding why remyelination fails in multiple sclerosis. Using the anti-NG2 monoclonal antibody to identify oligodendrocyte progenitor cells, we ha