## Abstract ILโ18 administration promotes innate immunity resulting in significant antitumor effects in multiple murine tumor models. Here, we examined the effector population mediating the innate immunity. Most NK cells and some NKT cells express ILโ18Rs without prior stimulation (65% positive in
โฆ LIBER โฆ
Endogenous natural killer cells do not play a role in antitumor effects induced by interleukin-2 in a syngeneic rat colon tumor model
โ Scribed by Martin Hagenaars; N. Geeske Ensink; Alexander M.M. Eggermont; Edo A. van der Velde; Cornelis J. H. van de Velde; Gert Jan Fleuren; Peter J.K. Kuppen
- Publisher
- Springer-Verlag
- Year
- 2000
- Tongue
- English
- Weight
- 235 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0340-7004
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## Interleukin -2-activated, cultured NK cells (A-NK) cells were adoptively transferred into a syngeneic rat liver-tumor model. The kinetics of tumor infiltration by NK cells, originating either from adoptively transferred or from endogenous sources, the localization of these cells in the tumor, a