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Endogenous 5-HT Tonically Inhibits Spontaneous Firing Activity of Dorsal Hippocampus CA1 Pyramidal Neurons Through Stimulation of 5-HT1A Receptors in Quiet Awake Rats: In Vivo Electrophysiological Evidence

✍ Scribed by Kimihiro Kasamo; Tadashi Suzuki; Koji Tada; Naoki Ueda; Emi Matsuda; Koichi Ishikawa; Takuya Kojima

Book ID: 114280712
Publisher: Nature Publishing Group
Year: 2001
Tongue: English
Weight: 348 KB
Volume: 24
Category: Article
ISSN: 1470-634X
DOI: 10.1016/s0893-133x(00)00181-0

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Endogenous 5-HT inhibits firing activity

Endogenous 5-HT inhibits firing activity of hippocampal CA1 pyramidal neurons during conditioned fear stress-induced freezing behavior through stimulating 5-HT1A receptors

✍ Koji Tada; Kimihiro Kasamo; Tadashi Suzuki; Yamato Matsuzaki; Takuya Kojima 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 128 KB

This study examines the activity of hippocampal CA 1 pyramidal neurons during conditioned fear stress (CFS)-induced freezing behavior in unanesthetized, unrestrained rats. The firing frequency of hippocampal CA 1 pyramidal neurons was significantly decreased when conditioned rats exhibited freezing