T h r e e instances of malignant teratomas with positive reaction for alphafetoprotein (AFP) are presented. Sequential evaluations in them revealed that the production rate of AFP closely paralleled the amount of the viable malignant tumor tissue which fluctuated in the course of the diseases. T w o
Endodermal sinus tumor of the ovary and alpha fetoprotein: A case report
โ Scribed by Dr. James H. Thomas; Dimitrios G. Panoussopoulos; William R. Jewell
- Publisher
- John Wiley and Sons
- Year
- 1977
- Tongue
- English
- Weight
- 739 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0022-4790
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โฆ Synopsis
Abstract
Yolk sac tumors of the ovary are associated with elevations in serum levels of alpha fetoprotein (AFP). Thus, an antigenic marker is provided for evaluating therapeutic results in selected patients. A patient with a pure endodermal sinus tumor of the ovary is presented who underwent serial determinations of AFP. The effectiveness and limitations of serial AFP levels as demonstrated by this case are discussed in addition to the surgical and chemotherapeutic management of patients with yolk sac tumor of the ovary.
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