Endocrine therapy testing of human breast cancers in the soft agar clonogenic assay
โ Scribed by C. Kent Osborne; Daniel D. Von Hoff; Kathryn Mullins
- Publisher
- Springer US
- Year
- 1985
- Tongue
- English
- Weight
- 670 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0167-6806
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Estrogen (ER) and progesterone (PgR) receptors were assayed by histochemistry in primary, recurrent, and metastatic breast cancer. Ligand-conjugates composed of 17P-estradiol and 1 lcu-hydroxyprogesterone covalently linked to bovine serum albumin and labelled with fluorescein isothiocyanate were emp
This review presents our experience with the use of estrogen receptors (ER) and progesterone receptors (PgR) in the prediction of response to endocrine therapy in stage IV breast cancer. Presence of ER (>3 fmoUmg cytosol protein) significantly predicted response to the antiestrogen tamoxifen and to
Histological sections obtained from 70 patients with breast cancer, all of whom had received endocrine therapy for metastatic or locally advanced disease, were assessed for specific immunocytochemical staining of oestrogen receptor and the oestrogen-induced protein pS2. There was also sufficient mat
## Abstract Fifty-five patients with locally advanced breast cancer treated with initial endocrine therapy have been followed up for periods of between 6 and 64 months (median 17 months) with regular clinical and radiological examination. The aim of the study was to evaluate the role of mammography