Endocrine pancreas of teleost fish: A model for interaction of islet hormones?

✍ Scribed by Plisetskaya, Erika M.

• Book ID: 102336534
• Publisher: John Wiley and Sons
• Year: 1990
• Tongue: English
• Weight: 489 KB
• Volume: 256
• Category: Article
• ISSN: 0022-104X
• DOI: 10.1002/jez.1402560410

✦ Synopsis

The structure of the teleost endocrine pancreas is unique in its tendency to form either a large accumulation of islet tissue (principal islet) or a similar accumulation, surrounded by a rim of exocrine tissue (Brockmann body). This morphological peculiarity constitutes a valuable model for investigation of islet hormones and their interactions. Understanding of the functional and molecular characteristics of the fish pancreas was slowed by the unavailability of purified piscine islet hormones. This obstacle has been overcome recently. Our experiments on the endocrine pancreas of salmon, Oncorhynchus sp., which we review here, can serve as an example of the advantages of using a teleost fish in studies of vertebrate pancreatic physiology and biochemistry.