Endocrine-Disrupting Chemicals: From Basic Research to Clinical Practice

✍ Scribed by Andrea C. Gore Phd (auth.), Andrea C. Gore Phd (eds.)

• Publisher: Humana Press
• Year: 2007
• Tongue: English
• Leaves: 361
• Series: Contemporary Endocrinology
• Edition: 1
• Category: Library

✦ Synopsis

Endocrine Disrupting Chemicals: From Basic Research to Clinical Practice is the first book that provides comprehensive coverage of the three most important themes in the field of EDC research: the basic biology of EDCs, particularly their effects on reproductive systems; EDC effects on humans and wildlife, including biomedical considerations; and potential interventions and practical advice for dealing with the problem of EDCs. This book presents a translational approach to EDC research, spanning both basic biology and clinical applications, and provides a critical link between the laboratory and the physicians’ office. Scientists and physicians engaged in EDC studies or practice will find that this volume offers insight across all areas of EDC research, including clarifying the mechanisms for EDC effects, understanding the adverse affects of EDCs on humans and wildlife, and offering solutions to the problems created by exposures to EDCs.

✦ Table of Contents

Front Matter....Pages 1-1
Introduction to Endocrine-Disrupting Chemicals....Pages 3-8
Endocrine Disruption and the Female....Pages 9-31
Endocrine Disruption in the Male....Pages 33-62
Endocrine-Disrupting Chemicals and the Brain....Pages 63-109
Heavy Metals as Endocrine-Disrupting Chemicals....Pages 111-133
Cellular Mechanisms of Endocrine Disruption....Pages 135-174
Endocrine Disruptors, Epigenetically Induced Changes, and Transgenerational Transmission of Characters and Epigenetic States....Pages 175-189
Front Matter....Pages 191-191
Implications of Thyroid Hormone Signaling Through the Phosphoinositide-3 Kinase for Xenobiotic Disruption of Human Health....Pages 193-202
Endocrine Disruption and Reproductive Outcomes in Women....Pages 203-223
Epidemiologic Evidence on the Relationship Between Environmental Endocrine Disruptors and Male Reproductive and Developmental Health....Pages 225-251
Human Exposures and Body Burdens of Endocrine-Disrupting Chemicals....Pages 253-268
Front Matter....Pages 269-269
Policy Implications of Endocrine-Disrupting Chemicals in Humans....Pages 271-287
Talking With Patients and the Public About Endocrine-Disrupting Chemicals....Pages 289-307
Community Interventions to Reduce Exposure to Chemicals with Endocrine-Disrupting Properties....Pages 309-328
What Can We Do About Endocrine-Disrupting Chemicals?....Pages 329-347

✦ Subjects

Endocrinology; Diabetes; Industrial Chemistry/Chemical Engineering; Biotechnology