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Endocervical Cancer Is Associated with an Increase in the Ligands and Receptors for Transforming Growth Factor-β and a Contrasting Decrease in p27Kip1

✍ Scribed by John Farley; Karen Gray; Lawrence Nycum; Margaret Prentice; Michael J. Birrer; Sonia B. Jakowlew


Book ID
112248187
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
303 KB
Volume
78
Category
Article
ISSN
0090-8258

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## BACKGROUND. The mechanism behind castration-induced apoptosis in prostate cells is unknown, but data from other species suggest that transforming growth factor ␤1 (TGF-␤1) may be involved. METHODS. By using quantitative RT-PCR and immunohistochemistry, expression of TGF-␤1 and its receptors typ