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Encoded combinatorial peptide libraries containing non-natural amino acids

โœ Scribed by Kerr, Janice M.; Banville, Steven C.; Zuckermann, Ronald N.


Book ID
127353152
Publisher
American Chemical Society
Year
1993
Tongue
English
Weight
376 KB
Volume
115
Category
Article
ISSN
0002-7863

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An unnatural peptide-based library, bound on a solid support, was screened for double-stranded-DNA (dsDNA)-binding ligands. For this purpose, fluorescein and rhodamine were used to label the single-stranded oligodeoxynucleotides. Beads containing products with affinity to dsDNA turned red in visible