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Enantiospecific Synthesis of Swainsonine, (1S, 2R, 8R, 8aR)-1,2,8-trihydroxyoctahydroindolizine, from D-mannose

✍ Scribed by G.W.J. Fleet; M.J. Gough; P.W. Smith


Publisher
Elsevier Science
Year
1984
Tongue
French
Weight
236 KB
Volume
25
Category
Article
ISSN
0040-4039

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(6S)-Methyl-l-swainsonine [(1R,2S,6S,8S,
✍ HΓ₯kansson, Anders E. ;Horne, Graeme ;Fleet, George W.J. ;Watkin, David J. πŸ“‚ Article πŸ“… 2006 πŸ› International Union of Crystallography 🌐 English βš– 302 KB

Methyl-l-swainsonine, C 9 H 17 NO 3 , together with the 6Repimer, was formed in a synthetic sequence in which there was an ambiguity in configuration at position C-6. This ambiguity was resolved by establishing the relative stereochemistry of the title compound by X-ray crystallographic analysis. Th