An enantiospecific synthesis of the antitumor marine sponge metabolite puupehedione (2a) and its C 8 -epimer 2b as their methylenedioxy derivatives 8a and 8b was achieved through concomitant O-allyl deprotection and electrocyclization of 20 derived from (-)-carvone.
Enantiospecific synthesis of (+)-paeonilactone C and (+)-paeoniflorigenone from R-(−)-carvone
✍ Scribed by Susumi Hatakeyama; Mitsuhiro Kawamura; Seiichi Takano; Hiroshi Irie
- Book ID
- 103402245
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- French
- Weight
- 210 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0040-4039
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Enantiocontrolled Formal Total Synthesis of Paeonilactone A and B from (S)-(+)-Carvone. -Compound (V), which is an intermediate in the synthesis of paeonilactone A and B, is prepared via stereoselective palladiumcatalyzed oxylactonization of diene (IV) as the key step. -(ROENN, M.;