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Enantiospecific synthesis of L-(3R; and 3S)-(β-D-ribofuranosyl)-pyroglutamic acids: Possible intermediates in C-nucleoside biosynthesis

✍ Scribed by Jack E. Baldwin; Robert M. Adlington; Nicholas G. Robinson

Book ID: 104216379
Publisher: Elsevier Science
Year: 1988
Tongue: French
Weight: 231 KB
Volume: 29
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)80100-8

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✦ Synopsis

The stereospecific addition of a glycine anion equivalent to a P-ribosyl acrylate is the key step in the enantiospecific synthesis of L-3-(P-&ibofuranosyl)-pyroglutamic acids, possible intermediates in C-nucleoside biosynthesis.

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