𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Enantiospecific first total synthesis of (+)-cis,anti,cis-3-hydroxy-1,8,12,12-tetramethyl-4-oxatricyclo[6.4.0.02,6]dodecan-9-yl senecioate, the optical antipode of a natural thapsane isolated from Thapsia villosa

✍ Scribed by A. Srikrishna; K. Anebouselvy


Publisher
Elsevier Science
Year
2003
Tongue
French
Weight
271 KB
Volume
44
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis


The enantiospecific first total synthesis of 10-hydroxy-10,11-epoxythapsan-5-yl senecioate (+)-1f, the enantiomer of the natural thapsane isolated from Thapsia villosa var minor, has been accomplished starting from (R)-carvone.