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Enantiospecific first total synthesis of (6S,7R)-silphiperfolan-6-ol

✍ Scribed by A. Srikrishna; Gopalasetty Nagaraju; Vishal M. Sheth


Book ID
113929290
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
362 KB
Volume
68
Category
Article
ISSN
0040-4020

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Enantiospecific synthesis of [7R,6S,5S,4
✍ G.S.C. Srikanth; Urlam MuraliKrishna; Girish K. Trivedi πŸ“‚ Article πŸ“… 2002 πŸ› Elsevier Science 🌐 French βš– 75 KB

A short and efficient synthesis of [7R,6S,5S,4R]-triacetoxy-(-)-goniotriol starting form D-glucose is described. A sequence of ring closing metathesis (RCM) followed by a PCC oxidation was used to construct the core six-membered a,b-unsaturated lactone moiety.