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Enantiospecific analysis of ibuprofen by high performance liquid chromatography: Determination of free and total drug enantiomer concentrations in serum and urine

✍ Scribed by S. C. Tan; S. H. D. Jackson; C. G. Swift; A. J. Hutt

Publisher
Springer
Year
1997
Tongue
English
Weight
887 KB
Volume
46
Category
Article
ISSN
0009-5893

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A high-performance liquid chromatographic analysis of phenylpropanolamine in human serum and urine without prior derivatization is presented. Using direct UV detection the method is sufficiently sensitive to detect 25 ng of drug/ml of serum or urine; the coefficients of variation at 25 ng/ml and 500