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Enantioseparation of chiral N-imidazole derivatives by electrokinetic chromatography using highly sulfated cyclodextrins: Mechanism of enantioselective recognition

✍ Scribed by Cécile Danel; Emmanuelle Lipka; Jean-Paul Bonte; Jean-François Goossens; Claude Vaccher; Catherine Foulon


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
171 KB
Volume
26
Category
Article
ISSN
0173-0835

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Enantioseparation of chiral benzimidazol
✍ Emmanuelle Lipka; Julie Charton; Marie-Pierre Vaccher; Marcia Folly-Klan; Jean-P 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 558 KB

## Abstract Baseline separation of 18 new substituted benzimidazole derivatives, potent AMP‐activated protein kinase (AMPK) activators, with one chiral center, was achieved by CD‐EKC using sulfated and highly sulfated CDs (SCDs and HS‐CDs) as chiral selectors. The influence of the type and concentr