Enantioselective Transfer Hydrogenation of Aliphatic Ketones Catalyzed by Ruthenium Complexes Linked to the Secondary Face of β-Cyclodextrin

✍ Scribed by Alain Schlatter; Wolf-D. Woggon

• Publisher: John Wiley and Sons
• Year: 2008
• Tongue: English
• Weight: 410 KB
• Volume: 350
• Category: Article
• ISSN: 1615-4150
• DOI: 10.1002/adsc.200700558

✦ Synopsis

Abstract

Ruthenium‐η‐arene complexes attached to the secondary face of β‐cyclodextrin catalyze the enantioselective reduction (ee up to 98%) of aliphatic and aromatic ketones in aqueous medium in the presence of sodium formate (HCOONa).