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Enantioselective Total Synthesis of the Cyclotryptamine Alkaloid Idiospermuline

โœ Scribed by Larry E. Overman; Emily A. Peterson


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
111 KB
Volume
115
Category
Article
ISSN
0044-8249

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โœ Priv.-Doz. Dr. Dietrich Spitzner; Prof. Dr. Ernest Wenkert ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 213 KB ๐Ÿ‘ 1 views

The tetrahedrane framework with R=tBu and the octabisvalene framework with R = CH3 presumably form because of steric reasons. Whereas the hydrocarbon 2 is highly strained, the arrangement in 1 is largely strain-free, based on the intermolecular contact distances. With other residues R the occurrenc