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Enantioselective synthesis of β-hydroxy-α-amino acid esters by aldol coupling using a chiral quaternary ammonium salt as catalyst

✍ Scribed by Manabu Horikawa; Jakob Busch-Petersen; E.J Corey

Book ID
104261419
Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
263 KB
Volume
40
Category
Article
ISSN
0040-4039

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✦ Synopsis

A variety of chiral fl-hydroxy-ct-amino acids and derivatives thereof can be synthesized enantioselectively using the aldol reaction of an aldehyde, the glycinate 1 and the cinchonidinederived catalyst 2, as indicated in Schemes I and 2 and Table 1.

📜 SIMILAR VOLUMES

Novel Cinchona Alkaloid Derived Ammonium
Novel Cinchona Alkaloid Derived Ammonium Salts as Catalysts for the Asymmetric Synthesis of β-Hydroxy α-Amino Acids via Aldol Reactions.
✍ Bing Ma; Jared L. Parkinson; Steven L. Castle 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 28 KB 👁 2 views

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