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Enantioselective synthesis of β-amino acids. 7. Preparation of enantiopure α-substituted β-amino acids from 1-benzoyl-2(S)-tert-butyl-3-methylperhydropyrimidin-4-one.1,2

✍ Scribed by Eusebio Juaristi; Delia Quintana; Margarita Balderas; Enrique García-Pérez


Book ID
108036466
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
796 KB
Volume
7
Category
Article
ISSN
0957-4166

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

Solid-phase synthesis of 3,7-disubstitut
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We report here the synthesis of 3,7-disubstituted perhydro-1,4-diazepine-2,5-diones from amino acids and b-amino acids using a backbone amide linker (BAL) as a cis-configuration inductor. We have optimized each steps of the synthesis on solid support using Mimotopes crowns.