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Enantioselective Synthesis of α-Quaternary Amino Acid Derivatives by Sequential Enzymatic Desymmetrization and Curtius Rearrangement of α,α-Disubstituted Malonate Diesters

✍ Scribed by Iosub, Violeta; Haberl, Anton R.; Leung, Jennifer; Tang, Michael; Vembaiyan, Kannan; Parvez, Masood; Back, Thomas G.


Book ID
120479899
Publisher
American Chemical Society
Year
2010
Tongue
English
Weight
914 KB
Volume
75
Category
Article
ISSN
0022-3263

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📜 SIMILAR VOLUMES


Enantioselective synthesis of α,α-disubs
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The sequential addition of two different nucleophiles to a tartaric acid-derived nitrile produced carbinamines. The adducts from chelation-controlled addition which are obtained in high diastereoselectivities and yields, were easily converted to ct,ct-disubstituted-t~-amino acids.

ChemInform Abstract: Enantioselective Sy
✍ D. M. SPERO; S. R. KAPADIA 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 36 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v