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Enantioselective Synthesis of the Unnatural Enantiomers of the Fungal Sesquiterpenoids Acorenone and Trichoacorenol

✍ Scribed by Nelson L. Brock; Jeroen S. Dickschat


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
574 KB
Volume
2011
Category
Article
ISSN
1434-193X

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## Abstract The accumulation of psychosine (galactosyl sphingosine) has been associated with the pathogenesis of Krabbe disease; however, the exact mechanism of its cytotoxicity remains unclear. Herein, we describe the synthesis of the unnatural enantiomer of erythro‐sphingosine, psychosine, and re