Enantioselective Synthesis of the Alcohol Moiety of Dolabriferol
✍ Scribed by Pelchat, Nicholas; Caron, Dave; Chênevert, Robert
- Book ID
- 127097326
- Publisher
- American Chemical Society
- Year
- 2007
- Tongue
- English
- Weight
- 104 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0022-3263
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Enantioselective construction of the protected carbocycle moiety of the anti-HIV drug carbovir was achieved in 11 steps from (S)-(-)-ethyl lactate. The two key steps are a Claisen [3+3] sigmatropic rearrangement of (3S,4E)-3-(4-methoxy-phenoxymethyl)-hex-4-enoic acid dimethylamide and next, a ruthen
was subjected to enantioselective Sharpless bis(hydroxyl-
## Abstract An enantioselective route to functionalized 3‐oxabicyclo‐[3.3.0]octane derivatives which can be used in hydroazulene synthesis is described. The configuration and conformation of the ketone 10 has been determined by ^1^H‐NMR spectroscopy and force‐field calculations.
was .msolved. with Pseudomqnas jluoye~pase and one of the enanttomers was convetted mto a hey mtermedtate in the synthests of mevmr .