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Enantioselective Synthesis of (−)-Platensimycin Oxatetracyclic Core by Using an Intramolecular Diels−Alder Reaction

✍ Scribed by Ghosh, Arun K.; Xi, Kai


Book ID
117990766
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
75 KB
Volume
9
Category
Article
ISSN
1523-7060

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Enantioselective synthesis and absolute
✍ Wolfgang Oppolzer; Dominique Dupuis; Giovanni Poli; Tony M. Raynham; Gérald Bern 📂 Article 📅 1988 🏛 Elsevier Science 🌐 French ⚖ 297 KB

Pulo'upone (1) was synthesized via an asymmetric, bornane-10,2-sultam-directed, intramolecular Diels-Alderaction (2 -+ 2) and a 2\_pyridylcuprate/allylacetate coupling (18 + I). The (6'R, 9'S, 13'R. 14'R)configuration of (-)-I follows from an X-ray diffraction analysis of the cycloaddition product