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Enantioselective Synthesis of Indanols from tert-Cyclobutanols Using a Rhodium-Catalyzed CC/CH Activation Sequence

✍ Scribed by Tobias Seiser; Olivia A. Roth; Nicolai Cramer


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
335 KB
Volume
121
Category
Article
ISSN
0044-8249

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Among numerous examples of transition-metal-mediated cyclization to obtain medium-sized ring compounds, [1] intramolecular hydroacylation provides the most promising way to prepare cyclopentanones from 4-pentenal through the CÀHbond activation of an aldehyde. [2, 3] However, its application has been