Enantioselective Synthesis of Coumarin Derivatives by PYBOX-DIPH-Zn(II) Complex Catalyzed Michael Reaction
✍ Scribed by Ray, Sumit K.; Singh, Pradeep K.; Molleti, Nagaraju; Singh, Vinod K.
- Book ID
- 118043826
- Publisher
- American Chemical Society
- Year
- 2012
- Tongue
- English
- Weight
- 545 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0022-3263
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The conjugate addition of propionate silylketcne acetal 1 to 2-carbomethoxy cyclopentenone is promoted by bis(oxazoline)-Cu(ll) complexes with high diastcreosclectivity and good enantiomeric excesses. The absolute configuration of the product can bc controlled by varying the copper counterion. A ca