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Enantioselective synthesis of Boc-protected norfuranomycins

✍ Scribed by Mikko Passiniemi; Ari M.P. Koskinen


Book ID
113930109
Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
346 KB
Volume
52
Category
Article
ISSN
0040-4039

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A new stereoselective synthesis of enantiomerically pure l-naphthylglycine has been developed. The source of chirality is the catalytic Sharpless epoxidation. Regioselective and stereospecific ring-opening of the corresponding epoxy alcohol is performed either with sodium azide or with benzhydrylami