Enantioselective Synthesis of a Key Intermediate in a New Process for Orlistat Using Asymmetric Hydrogenation and a Grignard Reagent Promoted Lactone Cyclization

✍ Scribed by Schwindt, Mark A.; Fleming, Michael P.; Han, Yeun-Kwei; Hodges, Lewis M.; Johnston, David A.; Micheli, Roger P.; Roberts, Chris R.; Snyder, Roger; Topping, Robert J.; Püntener, Kurt; Scalone, Michelangelo

• Book ID: 126902429
• Publisher: American Chemical Society
• Year: 2007
• Tongue: English
• Weight: 151 KB
• Volume: 11
• Category: Article
• ISSN: 1083-6160
• DOI: 10.1021/op060208q