Synthesis of substituted 3-hydroxy-4-alk
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Teodozyj Kolasa; Marvin J. Miller
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Article
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1987
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Elsevier Science
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French
β 189 KB
A short chemical process is described for the synthesis of optically active 3y roxy-4-alkoxycarbonyl-Z-azetidinones (R-lactams) from L-tartaric acid. Tartaric acid is an extremely useful and versatile member of the chiral pool. Since nearly any type of f+hydroxy acid can be converted to a 8-lactam (