𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Enantioselective steady-state kinetics of unbound disopyramide and its dealkylated metabolite in man

✍ Scribed by J. Hasselström; M. Enquist; J. Hermansson; R. Dahlqvist


Publisher
Springer
Year
1991
Tongue
English
Weight
428 KB
Volume
41
Category
Article
ISSN
0031-6970

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Comparative class 1 electrophysiologic a
✍ Lennart Bergfeldt; Karin Schenck-Gustafsson; Rune Dahlqvist 📂 Article 📅 1992 🏛 Springer US 🌐 English ⚖ 860 KB

During steady-state treatment with disopyramide, its main and active metabolite, mono-N-dealkylated disopyramide, was reported to reach concentrations that were equal to or higher than the parent drug in 25% of 70 evaluated patients. This metabolite has been found to have a more pronounced anticholi

Steady-state pharmacokinetics of the ena
✍ Jagdev Sidhu; Morten Priskorn; Mette Poulsen; Alain Segonzac; Gilles Grollier; F 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 165 KB 👁 2 views

The steady-state pharmacokinetics in serum and urine of the enantiomers of citalopram and its metabolites, demethylcitalopram (DCT) and didemethylcitalopram (DDCT), were investigated after multiple doses of rac-citalopram for 21 consecutive days (40 mg per day) to healthy human subjects who were ext