During steady-state treatment with disopyramide, its main and active metabolite, mono-N-dealkylated disopyramide, was reported to reach concentrations that were equal to or higher than the parent drug in 25% of 70 evaluated patients. This metabolite has been found to have a more pronounced anticholi
✦ LIBER ✦
Enantioselective steady-state kinetics of unbound disopyramide and its dealkylated metabolite in man
✍ Scribed by J. Hasselström; M. Enquist; J. Hermansson; R. Dahlqvist
- Publisher
- Springer
- Year
- 1991
- Tongue
- English
- Weight
- 428 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0031-6970
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