Enantioselective rhodium(I)-triethylamine catalyzed addition of potassium isopropenyl trifluoroborate to enones

✍ Scribed by Gojko Lalic; E.J. Corey

• Book ID: 104095485
• Publisher: Elsevier Science
• Year: 2008
• Tongue: French
• Weight: 181 KB
• Volume: 49
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/j.tetlet.2008.05.147

✦ Synopsis

A general process is reported for the highly enantioselective 1,4-addition of isopropenyl trifluoroborate to cyclic enones under catalysis by a chiral Rh(I) complex and triethylamine at room temperature.