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Enantioselective reduction of acetophenone by borane.chiral amine complexes

โœ Scribed by M.B. Eleveld; H. Hogeveen


Publisher
Elsevier Science
Year
1986
Tongue
French
Weight
232 KB
Volume
27
Category
Article
ISSN
0040-4039

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๐Ÿ“œ SIMILAR VOLUMES


ChemInform Abstract: Enantioselective Bo
โœ F.-Y. ZHANG; C.-W. YIP; A. S. C. CHAN ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 28 KB ๐Ÿ‘ 2 views

Enantioselective Borane Reduction of Ketones Catalyzed by Chiral Lanthanum Alkoxides. -The enantioselective reduction of simple unfunctionalized ketones (I) is achieved by borane in the presence of a preformed catalyst from (R)-binaphthol and lanthanum triisopropoxide. -(ZHANG,

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Optically pure B-hydroxysulfoximines were treated in toluene solution at -789~ with 2 equiv. of gaseous d i borane. The resulting borane complexes were used to reduce prochiral ketones at -78ยฐC; alcohols with optical purities ranging from 3 to 82% were obta i ned .