Enantioselective Recognition of Amino Acid by Differential Pulse Voltammetry in Molecularly Imprinted Monolayers Assembled on Au Electrodes
✍ Scribed by Shuangyan Huan; Guoli Shen; Ruqin Yu
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 94 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1040-0397
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✦ Synopsis
Abstract
An electrochemical sensor based on L‐cysteine SAM imprinted by L‐serine has been developed for the detection of L‐serine. The sensor shows some entantioselectivity toward L‐serine and a stable response establishes within 5 min. The peak current intensity of potassium ferricyanide quantified by differential pulse voltammetry (DPV) decreased linearly with increasing L‐serine concentration from 10 to 100 μM with a gradient of 20.91 nA μM^−1^. The detection limit was 4.32 μM. The coefficient of enantiometric selectivity of the molecularly imprinted SAM was about 3.0. Compounds with similar structure as serine caused much less response.