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Enantioselective Protonation of Catalytically Generated Chiral Enolates as an Approach to the Synthesis of α-Chloroesters

✍ Scribed by Reynolds, Nathan T.; Rovis, Tomislav


Book ID
120475996
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
59 KB
Volume
127
Category
Article
ISSN
0002-7863

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📜 SIMILAR VOLUMES


An Approach to Catalytic Enantioselectiv
✍ Pierre Riviere; Kenji Koga 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 517 KB

Protonationof prochirallithiumenolates(4), preparedfromracemic2substituted-1 -tetralones(2) via their silyl enolethers(3), withexcesssuccinimidein the presenceof lithiumbromideand0.2equivalentof a chiraltetmdentateamine((R)-1)in tolueneat -78'Cgaveopticallyactive2 in upto 83%ee. @1997 Elsevier Scien