✦ LIBER ✦
Enantioselective Protonation of a Simple Enol: Aminoalcohol-Catalyzed Ketonization of a Photochemically Produced 2-Methylinden-3-ol
✍ Scribed by Dr. Franpise Henin; Dr. Jacques Muzart; Prof. Dr. Jean-Pierre Pete; Anastase M'boungou-M'passi; Prof. Dr. Hermann Rau
- Book ID
- 101559764
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 365 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0044-8249
No coin nor oath required. For personal study only.
✦ Synopsis
J 17 18 of the main diastereomer (18) of 10a was determined by nuclear Overhauser enhancement (NOE) difference spec-tro~copy.['~I The cyclization 9a -+ 10 a may be explained by considering the reactive intermediates 15 and 16: intermediate 15 appears to be less favorable than 16 as a result of Table 2. Analytical data for the compounds 4, 12b (major diastereomer) and 18. 'HNMR: 270MHz. CDCI,, TMS as