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Enantioselective preparation of metoprolol and its major metabolites

✍ Scribed by Sang-Hun Jung; Pham Tuan Linh; Hee-Kyun Lim; Hyun-Ju Kim; Kyeong-Ho Kim; Jong-Seong Kang


Book ID
105672472
Publisher
Springer
Year
2000
Tongue
English
Weight
382 KB
Volume
23
Category
Article
ISSN
0253-6269

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Synthesis of labeled ambroxol and its ma
✍ Bachir Latli; Matt Hrapchak; Heinz-Karl Switek; Daniel M. Retz; Dhileepkumar Kri πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 French βš– 253 KB

## Abstract Ambroxol is a mucolytic agent used in the treatment of respiratory diseases. Herein, we report the synthesis of carbon‐14‐labeled ambroxol with the radioactive atom(s) either on the benzylic carbon or uniformly in the cyclohexyl ring with specific activities of 59 and 81 mCi/mmol, respe