Facile synthesis of l-Dopa tert-butyl es
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Takashi Ooi; Minoru Kameda; Hidenori Tannai; Keiji Maruoka
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Article
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2000
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Elsevier Science
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French
⚖ 94 KB
Facile asymmetric synthesis of L-Dopa and related amino acid esters has been achieved by phase-transfer catalysis of the rationally designed C 2 -symmetric chiral quaternary ammonium salts 1. The 'scale-up' experiment performed with 5.00 g of tert-butyl glycinate-benzophenone Schiff base (2) represe