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Enantioselective pharmacokinetics of mabuterol in rats studied using sequential achiral and chiral HPLC

✍ Scribed by Xiumei Lu; Pei Liu; Huashan Chen; Feng Qin; Famei Li


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
160 KB
Volume
19
Category
Article
ISSN
0269-3879

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## Abstract A specific, accurate, precise and reproducible high‐performance liquid chromatography (HPLC) method was developed for the estimation of ragaglitazar [(βˆ’) DRF 2725, NNC 61‐0029], a novel anti‐diabetic agent, in rat plasma. The assay procedure involved simple liquid/liquid extraction of r